abstract：:Eight diurnally active (06:00-23:00 h) subjects were adapted for 2 days to the room conditions where the experiments were performed. Blood sampling for adenosine metabolites and metabolizing enzymes was done hourly during the activity span and every 30 min during sleep. The results showed that adenosine and its catabo...

journal_title：Chronobiology international

authors： Chagoya de Sánchez V,Hernández-Muñoz R,Suárez J,Vidrio S,Yáñez L,Aguilar-Roblero R,Oksenberg A,Vega-González A,Villalobos L,Rosenthal L,Fernández-Cancino F,Drucker-Colín R,Díaz-Muñoz M

更新日期：1996-08-01 00:00:00

abstract：:The effects of short-term food deprivation on the serum and renal distribution and nephrotoxicity of tobramycin were studied in female Sprague-Dawley rats maintained on a 14-h light/10-h dark cycle (light on: 06:00). For the distribution study, a single injection of tobramycin (40 mg/kg, i.p.) was administered at 14:0...

journal_title：Chronobiology international

authors： Lin L,Grenier L,LeBrun M,Bergeron MG,Thibault L,Labrecque G,Beauchamp D

更新日期：1996-07-01 00:00:00

abstract：:Intense artificial light can phase-shift circadian rhythms and improve performance, sleep, and well-being during shiftwork simulations. In real shiftworkers, however, exposure to sunlight and other time cues may decrease the efficacy of light treatment, and occupational and family responsibilities may make it impracti...

journal_title：Chronobiology international

authors： Stewart KT,Hayes BC,Eastman CI

更新日期：1995-04-01 00:00:00

abstract：:Chronic sympathetic denervation of the pineal gland by bilateral removal of the superior cervical ganglia (SCG) was performed on female rats 30 days before impregnation. The offspring, maintained in the dark from birth, had disruption of the malate dehydrogenase circadian rhythm in the testes at 25 days of age. A dail...

journal_title：Chronobiology international

authors： Vermouth NT,Carriazo CS,Gallará RV,Carpentieri AR,Bellavía SL

更新日期：1995-02-01 00:00:00

abstract：:Phase-response experiments using 1-h light pulses (LPs) of 1,100 lux applied under constant dim light of 0.3 lux were conducted with common marmosets, Callithrix j. jacchus, in order to obtain a complete phase-response curve established according to the common experimental procedure in a diurnal primate. Maximal phase...

journal_title：Chronobiology international

authors： Wechselberger E,Erkert HG

更新日期：1994-10-01 00:00:00

abstract：:A double-blind randomized parallel-group trial was undertaken to evaluate the influence of the dosing time of sustained-release ketoprofen (SRK) on its acceptability and efficacy. The SRK was prescribed for 2 weeks (200 mg once a day) to 117 outpatients with osteoarthritis of the knee and/or hip. One group received SR...

journal_title：Chronobiology international

authors： Perpoint B,Mismetti P,Simitsidis S,Hocquart J,Rambaud C,Buchmuller A,Queneau P,Decousus H

更新日期：1994-04-01 00:00:00

abstract：:Two different medications, one assumed to be a tranquilizer and the other an antifatigue agent, were tested. Both were found to be ineffective and thus were viewed as placebos and named P1 and P2. The effect of P1 and P2 on the circadian rhythms of a set of variables (e.g., sleep/wake, oral temperature and grip streng...

journal_title：Chronobiology international

authors： Reinberg AE,Bicakova-Rocher A,Gorceix A,Ashkenazi IE,Smolensky MH

更新日期：1994-02-01 00:00:00

abstract：:In order to optimize chronotherapeutic schedules (designs), we examined the interindividual differences in chronopharmacologic effects of drugs with consideration of the following three factors: (a) inherited factors of direct relevance to chronopharmacology (genetic variability, gender-related differences) as well as...

journal_title：Chronobiology international

authors： Reinberg AE,Ashkenazi IE

更新日期：1993-12-01 00:00:00

abstract：:The pineal hormone melatonin is potentially useful in the treatment of disorders, especially sleep disorders, associated with circadian rhythm disturbance. We have examined its effects on sleep, mood, and behaviour in a double-blind, placebo-controlled study of a small group of police officers working spans of seven s...

journal_title：Chronobiology international

authors： Folkard S,Arendt J,Clark M

更新日期：1993-10-01 00:00:00

abstract：:Changes in the free-running period of the circadian rhythms of hamsters occur after single nonphotic events such as a 3-h pulse of running induced by being put in a novel wheel. These changes are mostly in the direction of longer periods, and can exceed 0.2 h; the magnitude of the effect depends on the circadian phase...

journal_title：Chronobiology international

authors： Mrosovsky N

更新日期：1993-08-01 00:00:00

abstract：:Genetic risk is a primary contributing factor to the predisposition of a newborn child to elevated blood pressure later in life. An index of this factor is needed to assess in the neonate the success or failure of preventive interventions instituted for the pregnant women. This index could be based on characteristics ...

journal_title：Chronobiology international

authors： Hermida RC,Fernández JR,Ayala DE,Mojón A,Rey A,Rodríguez-Cervilla J,Fernández-Lorenzo JR,Fraga JM

更新日期：1993-06-01 00:00:00

abstract：:The pharmacokinetics of naproxen was studied in 12 healthy male volunteers after a single oral dose of 500 mg at 10:00 and 22:00 h. Ingestion of drug at 22:00 h delayed the occurrence of peak serum levels (p < 0.0212). None of the other pharmacokinetic parameters exhibited any significant diurnal variations. ...

journal_title：Chronobiology international

authors： Rao BR,Rambhau D,Rao VV

更新日期：1993-04-01 00:00:00

abstract：:Field observations spanning 1 year of the visits of two bee species--Tetraglossula bigamica (Hymenoptera: Colletidae) and Pseudagapostemon brasiliensis (Hymenoptera: Halictidae)--to the flowers of Ludwigia elegans (Onagraceae) evinced the existence of circadian and circannual components in the rhythms of activity both...

journal_title：Chronobiology international

authors： Gimenes M,Benedito-Silva AA,Marques MD

更新日期：1993-02-01 00:00:00

abstract：:A physiological dose of orally administered melatonin shifts circadian rhythms in humans according to a phase-response curve (PRC) that is nearly opposite in phase with the PRCs for light exposure: melatonin delays circadian rhythms when administered in the morning and advances them when administered in the afternoon ...

journal_title：Chronobiology international

authors： Lewy AJ,Ahmed S,Jackson JM,Sack RL

更新日期：1992-10-01 00:00:00

abstract：:The circadian melatonin rhythm is highly reproducible and generally not easily altered. The few perturbations that are capable of significantly changing either the amplitude or the pattern of the 24-h melatonin rhythm are summarized herein. Aging alters cyclic melatonin production by decreasing the amplitude of the no...

journal_title：Chronobiology international

authors： Reiter RJ,Richardson BA

更新日期：1992-08-01 00:00:00

abstract：:Genetic analysis of Neurospora crassa has identified many mutants that affect the biological clock. In this article we review the cloning of two of these genes, frq and prd-4. Both genes were isolated using a chromosome walk technique. Subcloning experiments and subsequent Northern analysis of frq implicate the import...

journal_title：Chronobiology international

authors： Aronson BD,Johnson KA,Liu Q,Dunlap JC

更新日期：1992-06-01 00:00:00

abstract：:Twenty-four different laboratory parameters including the phagocytic activity (phagocytic index) of polymorphonuclear leukocytes (PMNs) and various hematologic variables were investigated in 13 young healthy men during Spring 1988 in Munich, Germany. Venous blood of these volunteers was obtained under standardized con...

journal_title：Chronobiology international

authors： Melchart D,Martin P,Hallek M,Holzmann M,Jurcic X,Wagner H

更新日期：1992-01-01 00:00:00

abstract：:Ninety-five nonresident girls of a private school volunteered for the study with the teachers' help as well as parental consent. Ages were approximately 8, 9, and 10 years. They were synchronized with diurnal activity from 0730 to 2100 h and nocturnal rest. Fatigue, drowsiness, and attention were self-rated using visu...

journal_title：Chronobiology international

authors： Guérin N,Boulenguiez S,Reinberg A,Di Costanzo G,Guran P,Touitou Y

更新日期：1991-01-01 00:00:00

abstract：:In 33 patients with heart failure (NYHA II-III), the 24-h blood pressure rhythm was examined before and after the titration period of two ACE inhibitors. Blood pressure was measured by the oscillometric method using the blood pressure monitor 90202 from SpaceLabs, Inc. The measurements were taken from 06:00 to 22:00 h...

journal_title：Chronobiology international

authors： Osterziel KJ,Dietz R,Lemmer B

更新日期：1991-01-01 00:00:00

abstract：:Circadian phase dependency in pharmacokinetics and hemodynamic effects on blood pressure and heart rate of different galenic formulations of nifedipine (immediate-release, sustained-release, and i.v. solution) were studied in healthy subjects or in hypertensive patients. Pharmacokinetics of immediate-release but not s...

journal_title：Chronobiology international

authors： Lemmer B,Nold G,Behne S,Kaiser R

更新日期：1991-01-01 00:00:00

abstract：:Groups of photorefractory female subtropical house sparrows, Passer domesticus, when treated with 6 weeks of a short photocycle (8L:16D) showed significant ovarian growth on their return to a long photocycle (15L:9D). A 6-hr photophase coupled with scotophase of varying durations does not terminate the refractory peri...

journal_title：Chronobiology international

authors： Ravikumar G,Tewary PD

更新日期：1990-01-01 00:00:00

abstract：:In two experiments, triazolam (2.5 and 1.5 mg/animal) failed to significantly enhance the rate of reentrainment of hamsters (Mesocricetus auratus) to an 8-hr advance of their light-dark cycle. Evidently the phase-shifting effects of triazolam are not robust. The animals did not run much in their wheels in response to ...

journal_title：Chronobiology international

authors： Mrosovsky N,Salmon PA

更新日期：1990-01-01 00:00:00

abstract：:The aim of this study was to demonstrate that a possible recurrence may pertain to migraine attacks (MAs). The study was carried out by checking the personal diaries of 30 migraine sufferers ("migraineurs") who carefully annotated the date of their MA over twelve consecutive months. The group was composed of 15 males ...

journal_title：Chronobiology international

authors： Cugini P,Romit A,Di Palma L,Giacovazzo M

更新日期：1990-01-01 00:00:00

abstract：:Circadian rhythmicity of the structural morphometric model of rat endocrine pancreas has been studied in 24 Wistar female rats, four months old, kept in LD 12:12. The following parameters were evaluated: the volume fractions of nucleus and cytoplasm of exocrine cells, the size distribution and number in unit tissue vo...

journal_title：Chronobiology international

authors： Sforza C,Morini M,Dolci C,Vizzotto L,Carandente F

更新日期：1990-01-01 00:00:00

abstract：:The circadian rhythms of food and water consumption, the number of feeding and drinking episodes, oxygen consumption, carbon dioxide production, respiratory quotient, gross motor activity, and body temperature were measured in male B6C3F1 mice that were fed ad libitum (AL) or fed a caloric-restricted diet (CR). The CR...

journal_title：Chronobiology international

authors： Duffy PH,Feuers RJ,Hart RW

更新日期：1990-01-01 00:00:00

abstract：:Twenty-two depressed subjects who met criteria for major depressive disorder were grouped according to their initial REM latency. Subjects with short (less than or equal to 60 min) initial REM latency were separated from those with normal (greater than 60 min) initial REM latency. Subjects with short initial REM laten...

journal_title：Chronobiology international

authors： Zammit GK,Pollak C,Rosenbaum AH,Roth T

更新日期：1990-01-01 00:00:00

abstract：:Groups of 20-45-day-old rats maintained on a light (0600-1800)/dark (1800-0600) regimen with food and water available ad libitum were studied for the effect of hypoxic hypoxia on the circadian rhythm of corneal epithelial mitosis and thymidine incorporation. In experiments conducted during the months of September and ...

journal_title：Chronobiology international

authors： Kwarecki K,Krawczyk J

更新日期：1989-01-01 00:00:00

abstract：:A preliminary study was conducted to evaluate the change in nocturnal concentrations of testosterone, luteinizing hormone, growth hormone, prolactin, thyroxine, and cortisol following a control day (no exercise) and on a day in which exercise was performed. Exercise consisted of 90 min of cycling at 70% of each subjec...

journal_title：Chronobiology international

authors： Hackney AC,Ness RJ,Schrieber A

更新日期：1989-01-01 00:00:00

abstract：:Bone sarcomatous cells derived from human malignant tumors were cultured. The mitotic index was recorded for 39 hr. When the cultured cells originated from patients with cancer disease before any chemotherapy, ultradian mitotic rhythms of a 6-9-hr period were detected, but in many cases only after a sensitive statisti...

journal_title：Chronobiology international

authors： Petrovic A,Oudet C,Stutzmann J

更新日期：1989-01-01 00:00:00

abstract：:Circadian rhythms in plants are liable to masking, i.e. alterations by environmental influencing agents. Experiments have been reported for both positive and negative masking, attributed to a Zeitgeber which may either increase or decrease the amplitude of a circadian rhythm (CR). In some instances, the CR may even be...

journal_title：Chronobiology international

authors： Vanden Driessche T,Guisset JL,Gaspar T,Kevers C,Koukkari WL

更新日期：1989-01-01 00:00:00

abstract：:It has been previously documented that aspirin induced gastric injury of healthy male volunteers was greater in the morning than in the evening. We have also reported that fasting gastric acid secretion rates and gastric retention times for solids were lower in the morning hours of the circadian cycle. We hypothesized...

journal_title：Chronobiology international

authors： Moore JG,Larsen KR,Goo RH,Bjorkman DJ

更新日期：1988-01-01 00:00:00

abstract：:In young healthy subjects salmon calcitonin (SCT), intranasally administered, increased in serum as a function of the drug administration time. The serum concentration of a 400 IU SCT dose monitored 10 min after dosing was statistically more significant when inhaled at 0000 than at other, more conventional, administra...

journal_title：Chronobiology international

authors： Tarquini B,Cavallini V,Cariddi A,Checchi M,Sorice V,Cecchettin M

更新日期：1988-01-01 00:00:00

abstract：:In Channa punctatus, a significant daily variation in hypothalamic 5-HT level and monoamine oxidase (MAO) activity was noticed in preparatory phase (February), but not in prespawning (May) or postspawning (November) phases. Hypothalamic dopamine (DA) and noradrenaline (NA), on the other hand, showed marked daily varia...

journal_title：Chronobiology international

authors： Khan IA,Joy KP

更新日期：1988-01-01 00:00:00

abstract：:Eight diurnally active (approximately 0730-1100 hr) adults (41-61 yr) suffering from nocturnal asthma volunteered for a double-blind, cross-over randomized study of a once-daily dosing (600-900 mg/24 hr) of Armophylline (Rorer s.a., France), a sustained-release theophylline given either at 0800 hr or 2000 hr for 8-day...

journal_title：Chronobiology international

authors： Reinberg A,Pauchet F,Ruff F,Gervais A,Smolensky MH,Levi F,Gervais P,Chaouat D,Abella ML,Zidani R

更新日期：1987-01-01 00:00:00

abstract：:In this paper, a peptic ulcer is considered from the perspective that it is representative of a heterogeneous group of multifactorial determined or influenced disorders having a common pathomorphologic expression. This heterogeneity involves pathophysiological attributes, including both functional (including secretory...

journal_title：Chronobiology international

authors： Tarquini B,Vener KJ

更新日期：1987-01-01 00:00:00

abstract：:Circadian rhythms of plasma insulin, cortisol, and glucose concentrations were examined in scotosensitive (reproductively sensitive to inhibitory effects of short daylengths) and scotorefractory male and female Syrian hamsters (Mesocricetus auratus) maintained on short (LD 10:14) and long (LD 14:10) daylengths. The ba...

journal_title：Chronobiology international

authors： de Souza CJ,Meier AH

更新日期：1987-01-01 00:00:00

abstract：:Turnip moths, Agrotis segetum (Schiff.) (Lepidoptera: Noctuidae), were held in a transparent plastic box with a window opening to a rotating paper drum upon which the females could lay eggs. A novel fraction collector, consisting of a standard 24-hr wall timer and simple electronic circuit, served to rotate the paper ...

journal_title：Chronobiology international

authors： Byers JA

更新日期：1987-01-01 00:00:00

abstract：:Twenty-one children aged 5-6 years (mean age: 71.2 months; S.D. = 2.7) were videotaped in 4 different kindergartens throughout the school day for a period of one week. Eighteen of these children were then followed up after the summer holidays and videotaped for one week while attending the first year of primary school...

journal_title：Chronobiology international

authors： Koch P,Montagner H,Soussignan R

更新日期：1987-01-01 00:00:00

abstract：:Thirty-six undergraduate subjects were divided into 'larks' and 'owls' by median split using the morningness test devised by Horne and Ostberg. Each was given a battery of two performance tests at six times of day, in a design that counter-balanced for practice effects. Oral temperatures were also recorded. Slight (1 ...

journal_title：Chronobiology international

authors： Monk TH,Leng VC

更新日期：1986-01-01 00:00:00

abstract：:Specific binding of [3H]-imipramine in the rat suprachiasmatic nuclei, occipital cortex and caudate putamen underwent significant and replicable changes throughout 24 hr under a light-dark cycle or under constant conditions. Daily variations were also found in the medial and dorsal raphe nuclei and the lateral hypotha...

journal_title：Chronobiology international

authors： Kraeuchi K,Wirz-Justice A,Morimasa T,Suetterlin-Willener R,Feer H

更新日期：1986-01-01 00:00:00